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hEtG is a marker for alcohol intake over a longer period, able to approximately identify drinking habits in the past 3 to 6 months and differentiate between minimal or none, occasional moderate, and excessive alcohol consumption 32,39

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Interestingly, in contrast to CAFs, YAP nuclear intensity exhibits a significant decrease in both ductal carcinoma in situ and in invasive ductal carcinomas [88, 89]